Neurofibromatosis is a complex and multi-systemic genetic disorder that can prove challenging for a general practitioner. With the advancement through clinical research, the management and treatment guidelines for adults with Neurofibromatosis type 1 (NF1) and NF2-Related Schwannomatosis (formerly known as NF2) have been updated.

Management Guidelines for Adults with Neurofibromatosis Type 1 (NF1)

These guidelines offer healthcare providers essential recommendations for the care and management of adults with NF1. Regular annual assessments are crucial, focusing on blood pressure, bone health, and monitoring for neurological and psychological complications. Patients with NF1 are at risk for various complications, including hypertension, scoliosis, and an increased risk of breast cancer.

Management Guidelines for Adults with Neurofibromatosis Type 2 (NF2-SWN)

These guidelines provide comprehensive recommendations for healthcare professionals managing patients with NF2-related schwannomatosis (formerly known as NF2). They emphasize the importance of regular assessments and a multidisciplinary approach to address the complex nature of this condition, which affects the nervous system through tumours such as schwannomas, meningiomas, and ependymomas. The document focuses on essential areas including monitoring neurological symptoms, managing hearing and vision impairments, addressing pain and mobility issues, and providing psychological support. It also includes referral recommendations to specialists for optimal care and long-term management.

We are grateful to Nerve Tumours UK and NF2 BioSolutions for their editing assistance.